Ongoing Clinical Trials Ongoing Clinical Trials

Ongoing Clinical Trials

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We inform you of the clinical trials that are being conducted by K-MASTER Precision Medicine Project Group.

Number Protocol
No.
Research Title Carcinoma Target Gene Clinical
Trial Drug
PI Institution Progress
Status
Number of Subjects to be enrolled
11 KM-12 Phase II Study of PDR001 in Combination With MCS110 in Patients With Squamous Cell Carcinoma of the Esophagus Esophagus cancer single nucleotide varations (SNVs) and copy number changes MCS110, PDR001 Yonsei Cancer Center registering 0/45
12 KM-13 A two part, phase IB/II, open label, single-arm, multi-center study to evaluate the safety and efficacy of VARLITINIB in combination with weekly PACLITAXEL in EGFR/HER2 co-expressing advanced or metastatic gastric cancer patients. Gastric cancer EGFR, HER-2 Varlitinib, Paclitaxel Yonsei Cancer Center registering 0/67
13 KM-14 An open label, single-arm, multi-center phase II study to evaluate the safety and efficacy of Herzuma® in combination with Paclitaxel in HER2-positive recurrent/metastatic urothelial carcinoma Urinary epithelial cell cancer HER-2 Trastuzumab, Paclitaxel Seoul National University Hospital registering 5/27
14 KM-19 Randomized phase 2 study pembrolizumab q12 weeks versus q3 weeks in NSCLC with clinical benefit to pembrolizumab monotherapy Non-small cell lung cancer n Pembrolizumab Samsung Medical Center preparing 0/152